Complications after parathyroidectomy. Fractures from low calcium and magnesium convulsions.
نویسندگان
چکیده
symptoms are mild, the hypocalcaemia temporary, and treatment is not required. In a few, those with renal disease, bone disease or steatorrhoea, the hypocalcaemia is likely to be severe and need treatment. The routine management of this type of patient has been described by Dent (1962). We have recently studied two patients who had generalised convulsions after parathyroidectomy despite this routine treatment. The first patient, who had primary hyperparathyroidism with severe bone disease, developed hypomagnesaemia in addition to hypocalcaemia. The second patient underwent total parathyroidectomy for renal osteodystrophy secondary to polycystic disease of the kidneys, and developed severe hypocalcaemia which failed to respond until aluminium hydroxide was added to the routine therapy of calcium and vitamin D. In both patients severe tetany with convulsions caused multiple fractures. We wish to record these patients and make suggestions which should improve treatment after
منابع مشابه
Magnesium metabolism in primary hyperparathyroidism.
1. Magnesium metabolism has been studied in forty-eight patients with primary hyperparathyroidism. Metabolic balance studies were undertaken in forty-three untreated patients and in fifteen patients after parathyroidectomy. The data obtained are compared with the pattern of magnesium metabolism in healthy adults, as established by analysis of collected nutritional studies. The renal handling of...
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Urinary magnesium and pH are known to modulate urinary calcium excretion, but the mechanisms underlying these relationships are unknown. In this study, the data from 17 clinical trials in which urinary magnesium and pH were pharmacologically manipulated were analyzed, and it was found that the change in urinary calcium excretion is directly proportional to the change in magnesium excretion and ...
متن کاملTetany despite normocalcaemia and normomagnesaemia following parathyroidectomy.
Two patients with long-standing hyperparathyroidism due to a parathyroid adenoma are described. Both had severe osteitis fibrosa cystica and a proximal myopathy. Both were treated with alfacalcidol (2 micrograms/day) prior to and following parathyroidectomy, and infused with calcium gluconate following the operation. Plasma total and ionized calcium and magnesium concentrations were maintained ...
متن کاملApplication of total parathyroidectomy with auto-transplantation for uremia secondary hyperparathyroidism treatment.
BACKGROUND Secondary hyperparathyroidism (sHPT) is a common acquired disorder in patients with chronic renal failure. Despite the development of new therapeutic agents, a majority of patients will require parathyroidectomy. The aim of this study was to evaluate total parathyroidectomy with auto-transplantation of trace amounts of parathyroid tissue as a surgical option in uremia sHPT treatment....
متن کاملThe Excretion of Calcium and Magnesium after Parathyroidectomy
Within the past few years evidence has gradually accumulated, both direct and indirect, indicating some definite relation, the nature of which is as yet quite obscure, between the kations of calcium salts and certain forms of muscle irritability. The observations recorded may be summarized as follows : ( I ) Abnormal muscular twitchings and contractions may be brought about in an organism by a ...
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ورودعنوان ژورنال:
- The Journal of bone and joint surgery. British volume
دوره 48 1 شماره
صفحات -
تاریخ انتشار 1966